For years Bryan has been excited about the potential of computational data bases like SciDB to provide fast analytics of truly massive data sets. I have seen Bryan give this talk and it is well worth your time. In addition he has added Rstudio and Shiny to his talk which makes this a must go meet up in Boston on Wednesday night. Shiny has really enhance the ability to communicate results to non-experts through interactive visualizations that are easy to create and modify.
Here is the abstract to his talk: